CRIP3

Across TCGA patient cohorts, CRIP3 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CRIP3-associated genes across cancer lineages are eEF2, PCNA, and TFRC. Each is linked with CRIP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CRIP3-to-partner and partner-to-CRIP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by CRIP3-low versus CRIP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRIP3→partner) and Y-score (partner→CRIP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.558	+3.000	.006	.037	3	1
UCEC	PCNA →	+0.291	+3.000	.020	.037	3	1
UCEC	TFRC →	+0.686	+3.000	.025	.037	3	1
UCEC	Di-Ras3 →	-0.180	-3.000	.035	.037	2	1
UCEC	ETS-1 →	+0.371	+3.000	.044	.037	1	1
UCEC	MEK1 →	+0.540	+3.000	.010	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

eEF2 by CRIP3 expression — UCEC

Explore this box plot interactively →