CRIM1

Across TCGA patient cohorts, CRIM1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,624 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CRIM1-associated proteins across cancer lineages are RFC1_T506, ASAP2_S701, and ARHGEF17. Each is linked with CRIM1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CRIM1-to-partner and partner-to-CRIM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRIM1 versus RFC1_T506 in BRCA, with a Pearson correlation of -0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRIM1→partner) and Y-score (partner→CRIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RFC1_T506 →	-0.870	-0.979	.001	<.001	3	6
OV	ASAP2_S701 →	+0.624	+0.649	.002	.008	3	6
CCRCC	ARHGEF17 →	+0.256	+0.450	<.001	<.001	3	5
HNSC	LAMA5 →	+0.391	+0.577	.001	.003	3	5
PDAC	RSU1 →	+0.292	+0.469	<.001	<.001	3	5
UCEC	SNTB2 →	+0.303	+0.452	.007	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,624 associations by consensus.

CRIM1 vs RFC1_T506 — BRCA

Explore this scatter interactively →