CRIM1

Across TCGA patient cohorts, CRIM1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,794 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRIM1-associated genes across cancer lineages are CAV1, CRIM1-DT, and SUZ12. Each is linked with CRIM1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CRIM1-to-partner and partner-to-CRIM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRIM1 versus CAV1 in LSCC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRIM1→partner) and Y-score (partner→CRIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CAV1 →	+1.140	+0.262	<.001	<.001	3	4
BRCA	CRIM1-DT →	+0.908	+0.475	<.001	<.001	3	4
UCEC	SUZ12 →	-0.454	-0.450	.009	.005	3	4
HNSC	LINC02210 →	-0.578	-0.517	<.001	<.001	3	4
BRCA	FOXM1 →	-0.858	-0.378	.007	.003	3	3
BRCA	CDCA3 →	-0.678	-0.441	.007	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,794 associations by consensus.

CRIM1 vs CAV1 — LSCC

Explore this scatter interactively →