CRIM1

Across TCGA cell cohorts, CRIM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,215 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CRIM1-associated GO terms across cancer lineages are Positive regulation of focal adhesion assembly, Regulation of cell-matrix adhesion, and Regulation of hippo signaling. Each is linked with CRIM1 in more than 15 cancer types. Because this analysis shows association rather than direction, both CRIM1-to-partner and partner-to-CRIM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of focal adhesion assembly grouped by CRIM1-low versus CRIM1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRIM1→partner) and Y-score (partner→CRIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of focal adhesion assembly →	+0.220	+3.391	<.001	<.001	3	16
BONE	Regulation of cell-matrix adhesion →	+0.140	+2.747	<.001	<.001	3	16
STOMACH	Regulation of hippo signaling →	+0.133	+2.977	<.001	<.001	3	15
BONE	Regulation of cell-substrate junction assembly →	+0.147	+2.988	<.001	<.001	3	14
BONE	Regulation of cell-substrate adhesion →	+0.118	+2.613	<.001	<.001	3	14
BONE	Positive regulation of cell-substrate adhesion →	+0.135	+2.770	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,215 associations by consensus.

Positive regulation of focal adhesion assembly by CRIM1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →