CRHR2

Across TCGA patient cohorts, CRHR2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,503 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRHR2-associated genes across cancer lineages are FPR2, BCL2A1, and TMSB10. Each is linked with CRHR2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CRHR2-to-partner and partner-to-CRHR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRHR2 versus FPR2 in PDAC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRHR2→partner) and Y-score (partner→CRHR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	FPR2 →	-0.920	-0.334	<.001	.002	3	5
GBM	BCL2A1 →	-1.307	-0.359	<.001	.001	3	5
BRCA	TMSB10 →	-0.636	-0.255	<.001	<.001	3	4
HNSC	TNNC1 →	+2.117	+0.308	<.001	<.001	3	4
GBM	MOAP1 →	+0.552	+0.393	<.001	<.001	3	4
GBM	ADGRE2 →	-0.660	-0.299	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,503 associations by consensus.

CRHR2 vs FPR2 — PDAC

Explore this scatter interactively →