CRHR1

Across TCGA patient cohorts, CRHR1 mutation is significantly associated with the RNA expression of many other genes, with 1,516 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CRHR1-associated genes across cancer lineages are RN7SL43P, PRIM1, and MIR6846. Each is linked with CRHR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CRHR1-to-partner and partner-to-CRHR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL43P grouped by CRHR1-low versus CRHR1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRHR1→partner) and Y-score (partner→CRHR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL43P →	+0.134	+4.269	<.001	.002	3	3
LUSC	PRIM1 →	+0.691	+3.494	.001	.002	3	3
LIHC	MIR6846 →	+0.328	+4.676	<.001	.004	3	2
CESC	TRAJ58 →	+0.428	+3.874	<.001	.006	3	2
CESC	SRSF6P1 →	+0.054	+4.384	<.001	.008	3	2
CESC	LINC01445 →	+0.028	+4.384	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,516 associations by consensus.

RN7SL43P by CRHR1 expression — CESC

Explore this box plot interactively →