CRHR1

Across TCGA cell cohorts, CRHR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,668 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CRHR1-associated GO terms across cancer lineages are Regulation of corticosterone secretion, Purine nucleoside triphosphate metabolic process, and Purine ribonucleoside triphosphate metabolic process. Each is linked with CRHR1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CRHR1-to-partner and partner-to-CRHR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of corticosterone secretion grouped by CRHR1-low versus CRHR1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRHR1→partner) and Y-score (partner→CRHR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of corticosterone secretion →	-0.312	-1.105	<.001	.002	2	10
OVARY	Purine nucleoside triphosphate metabolic process →	+0.087	+1.073	<.001	.003	3	8
OVARY	Purine ribonucleoside triphosphate metabolic process →	+0.086	+1.074	<.001	.003	3	8
OVARY	ATP metabolic process →	+0.084	+1.027	.001	.006	3	8
OVARY	ATP synthesis coupled electron transport →	+0.094	+1.027	.001	.007	3	7
OVARY	Mitochondrial ATP synthesis coupled electron transport →	+0.094	+1.027	.001	.007	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,668 associations by consensus.

Regulation of corticosterone secretion by CRHR1 expression — OVARY

Explore this box plot interactively →