CRHBP

Across TCGA patient cohorts, CRHBP RNA expression is significantly associated with the protein abundance of many other proteins, with 19,734 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRHBP-associated proteins across cancer lineages are HEATR1, PRKG1, and WDR36. Each is linked with CRHBP in more than 6 cancer types. Because this analysis shows association rather than direction, both CRHBP-to-partner and partner-to-CRHBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRHBP versus HEATR1 in PDAC, with a Pearson correlation of -0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRHBP→partner) and Y-score (partner→CRHBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	HEATR1 →	-0.270	-0.378	.002	<.001	3	7
OV	PRKG1 →	+0.709	+0.302	<.001	.007	3	7
COAD	WDR36 →	-0.255	-0.183	<.001	<.001	3	6
CCRCC	RPS3A →	-0.197	-0.666	<.001	.001	3	6
BRCA	RSL1D1 →	-0.412	-0.349	<.001	<.001	3	6
COAD	MYH11 →	+0.982	+0.176	.001	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,734 associations by consensus.

CRHBP vs HEATR1 — PDAC

Explore this scatter interactively →