CRHBP

Across TCGA patient cohorts, CRHBP protein abundance is significantly associated with the RNA expression of many other genes, with 4,801 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRHBP-associated genes across cancer lineages are CYP3A5, CUEDC2, and FAM131C. Each is linked with CRHBP in more than 1 cancer types. Because this analysis shows association rather than direction, both CRHBP-to-partner and partner-to-CRHBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRHBP versus CYP3A5 in BRCA, with a Pearson correlation of -0.91.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRHBP→partner) and Y-score (partner→CRHBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CYP3A5 →	-0.940	-0.606	.002	.001	3	2
BRCA	CUEDC2 →	+1.120	+0.606	.002	.001	3	2
BRCA	FAM131C →	+1.990	+0.606	.003	.001	3	2
CCRCC	FAM110D →	+0.743	+0.464	<.001	<.001	3	2
GBM	TTLL11-IT1 →	+0.289	+0.470	.002	.001	3	2
GBM	ERC2-IT1 →	+0.622	+0.623	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,801 associations by consensus.

CRHBP vs CYP3A5 — BRCA

Explore this scatter interactively →