Across TCGA cell cohorts, CRELD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,550 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CRELD2-associated GO terms across cancer lineages are GDP-mannose biosynthetic process, Lytic vacuole organization, and Lysosome organization. Each is linked with CRELD2 in more than 12 cancer types. Because this analysis shows association rather than direction, both CRELD2-to-partner and partner-to-CRELD2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRELD2→partner) and Y-score (partner→CRELD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GDP-mannose biosynthetic process →	+0.141	+0.983	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Lytic vacuole organization →	+0.071	+1.115	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Lysosome organization →	+0.071	+1.115	<.001	<.001	3	12
SKIN	Multi-pass transmembrane protein insertion into ER membrane →	+0.123	+1.083	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.076	+1.203	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Protein N-linked glycosylation →	+0.077	+1.139	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,550 associations by consensus.

Exploration

CRELD2 survival (RNA) · tumor vs normal (RNA) · all CRELD2 data types