Across TCGA cell cohorts, CRELD2 mutation is significantly associated with the mutation status of many other genes, with 4,418 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CRELD2-associated genes across cancer lineages are RPS6KA4, LRRN1, and CHD7. Each is linked with CRELD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CRELD2-to-partner and partner-to-CRELD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRELD2→partner) and Y-score (partner→CRELD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	RPS6KA4 →	+2.830	+3.548	.009	.009	1	3
SKIN	LRRN1 →	+3.316	+3.906	.004	.004	1	3
UPPER_AERODIGESTIVE_TRACT	CHD7 →	+4.392	+4.954	.008	.008	1	3
BLOOD_Leukemia	TAS1R1 →	+3.479	+4.932	.002	.002	1	3
BLOOD_Leukemia	UBE2O →	+3.020	+4.545	.004	.004	1	3
BLOOD_Leukemia	ARID3B →	+4.157	+5.430	<.001	<.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,418 associations by consensus.

Exploration

CRELD2 survival (RNA) · tumor vs normal (RNA) · all CRELD2 data types