CRELD1

Across TCGA cell cohorts, CRELD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,263 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CRELD1-associated GO terms across cancer lineages are Protein polyglycylation, ER-nucleus signaling pathway, and Regulation of macroautophagy. Each is linked with CRELD1 in more than 13 cancer types. Because this analysis shows association rather than direction, both CRELD1-to-partner and partner-to-CRELD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein polyglycylation grouped by CRELD1-low versus CRELD1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRELD1→partner) and Y-score (partner→CRELD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein polyglycylation →	+1.453	+1.999	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	ER-nucleus signaling pathway →	+0.101	+2.300	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of macroautophagy →	+0.061	+1.726	<.001	.001	2	14
OVARY	ERAD pathway →	+0.092	+1.077	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Protein targeting →	+0.049	+1.280	<.001	<.001	3	13
BLOOD_Lymphoma	Negative regulation of myoblast fusion →	+0.118	+0.845	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,263 associations by consensus.

Protein polyglycylation by CRELD1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →