CREG2

Across TCGA patient cohorts, CREG2 protein abundance is significantly associated with the RNA expression of many other genes, with 247 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CREG2-associated genes across cancer lineages are YY1, DNTTIP1, and GAR1. Each is linked with CREG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CREG2-to-partner and partner-to-CREG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CREG2 versus YY1 in GBM, with a Pearson correlation of -0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CREG2→partner) and Y-score (partner→CREG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	YY1 →	-0.418	-1.283	.005	<.001	3	1
GBM	DNTTIP1 →	-0.413	-0.971	.002	.001	3	1
GBM	GAR1 →	-0.421	-1.031	.005	.009	3	1
GBM	AMBRA1 →	-0.278	-0.968	.002	.001	3	1
GBM	NUP98 →	-0.386	-1.118	.009	.004	3	1
GBM	PRDM4 →	-0.275	-0.859	.006	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 247 associations by consensus.

CREG2 vs YY1 — GBM

Explore this scatter interactively →