CREG2

Across TCGA cell cohorts, CREG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,173 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CREG2-associated GO terms across cancer lineages are Plasma membrane organization, Regulation of proteolysis, and Regulation of protein import into nucleus. Each is linked with CREG2 in more than 9 cancer types. Because this analysis shows association rather than direction, both CREG2-to-partner and partner-to-CREG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Plasma membrane organization grouped by CREG2-low versus CREG2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CREG2→partner) and Y-score (partner→CREG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Plasma membrane organization →	+0.104	+1.847	<.001	.002	3	10
BREAST	Regulation of proteolysis →	+0.092	+0.875	<.001	<.001	3	9
OESOPHAGUS	Regulation of protein import into nucleus →	+0.086	+2.116	<.001	<.001	3	8
STOMACH	Positive regulation of proteolysis →	+0.136	+1.811	<.001	<.001	3	8
OESOPHAGUS	Cell-substrate junction assembly →	+0.226	+1.768	.001	.003	3	8
OESOPHAGUS	Cell-substrate junction organization →	+0.203	+1.947	.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,173 associations by consensus.

Plasma membrane organization by CREG2 expression — URINARY_TRACT

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