CREBZF

Across TCGA cell cohorts, CREBZF RNA expression is significantly associated with the go_rna of many other GO terms, with 4,596 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CREBZF-associated GO terms across cancer lineages are Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, and Positive regulation of intracellular estrogen receptor signaling pathway. Each is linked with CREBZF in more than 17 cancer types. Because this analysis shows association rather than direction, both CREBZF-to-partner and partner-to-CREBZF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway grouped by CREBZF-low versus CREBZF-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CREBZF→partner) and Y-score (partner→CREBZF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.134	+2.009	<.001	<.001	3	18
BONE	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.154	+1.527	<.001	<.001	3	18
LUNG_SCLC	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.187	+1.082	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.138	+1.818	<.001	<.001	3	17
BONE	Pre-mRNA catabolic process →	+0.239	+1.379	<.001	<.001	3	17
LUNG_SCLC	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.176	+0.883	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,596 associations by consensus.

Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway by CREBZF expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →