CREBBP

Across TCGA patient cohorts, CREBBP RNA expression is significantly associated with the protein abundance of many other proteins, with 14,797 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CREBBP-associated proteins across cancer lineages are SMC1A, SPIN1, and BUB3. Each is linked with CREBBP in more than 4 cancer types. Because this analysis shows association rather than direction, both CREBBP-to-partner and partner-to-CREBBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CREBBP versus SMC1A in GBM, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CREBBP→partner) and Y-score (partner→CREBBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SMC1A →	+0.261	+0.337	<.001	<.001	3	5
HNSC	SPIN1 →	+0.374	+0.765	<.001	<.001	3	5
LSCC	BUB3 →	+0.314	+0.566	<.001	<.001	3	5
BRCA	MAZ →	+0.399	+0.694	<.001	<.001	3	5
COAD	USP7 →	+0.222	+0.782	.004	.009	3	5
LUAD	RPL26 →	-0.531	-0.594	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,797 associations by consensus.

CREBBP vs SMC1A — GBM

Explore this scatter interactively →