CREB5

Across TCGA patient cohorts, CREB5 protein abundance is significantly associated with the RNA expression of many other genes, with 8,074 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CREB5-associated genes across cancer lineages are FAM126A, ZEB1, and TCF4. Each is linked with CREB5 in more than 2 cancer types. Because this analysis shows association rather than direction, both CREB5-to-partner and partner-to-CREB5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CREB5 versus FAM126A in BRCA, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CREB5→partner) and Y-score (partner→CREB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FAM126A →	+0.704	+0.497	.001	.003	3	3
BRCA	ZEB1 →	+1.071	+0.598	<.001	.001	3	3
BRCA	TCF4 →	+1.093	+0.736	<.001	<.001	3	3
LSCC	SYNDIG1 →	+1.498	+0.567	<.001	.004	3	2
BRCA	SRPX2 →	+1.153	+0.716	<.001	.004	3	2
LSCC	CTSH →	-0.745	-0.602	.006	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,074 associations by consensus.

CREB5 vs FAM126A — BRCA

Explore this scatter interactively →