CREB5

Across TCGA cell cohorts, CREB5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,904 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CREB5-associated GO terms across cancer lineages are Potassium ion transport, Regulation of extrinsic apoptotic signaling pathway via death domain receptors, and Regulation of T-helper 17 cell differentiation. Each is linked with CREB5 in more than 9 cancer types. Because this analysis shows association rather than direction, both CREB5-to-partner and partner-to-CREB5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Potassium ion transport grouped by CREB5-low versus CREB5-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CREB5→partner) and Y-score (partner→CREB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Potassium ion transport →	-0.057	-1.278	.002	.001	3	10
BONE	Regulation of extrinsic apoptotic signaling pathway via death domain receptors →	+0.157	+1.602	<.001	<.001	3	9
LIVER	Regulation of T-helper 17 cell differentiation →	+0.119	+2.091	<.001	<.001	3	9
BONE	Regulation of peptidyl-serine phosphorylation of STAT protein →	+0.187	+1.738	<.001	<.001	3	9
BREAST	Positive regulation of cytoskeleton organization →	+0.063	+1.085	<.001	.001	3	9
STOMACH	Constitutive secretory pathway →	+0.093	+1.419	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,904 associations by consensus.

Potassium ion transport by CREB5 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →