CREB3L4

Across TCGA patient cohorts, CREB3L4 protein abundance is significantly associated with the RNA expression of many other genes, with 4,552 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CREB3L4-associated genes across cancer lineages are RUVBL1, HBA2, and HBB. Each is linked with CREB3L4 in more than 2 cancer types. Because this analysis shows association rather than direction, both CREB3L4-to-partner and partner-to-CREB3L4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CREB3L4 versus RUVBL1 in BRCA, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CREB3L4→partner) and Y-score (partner→CREB3L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RUVBL1 →	-0.521	-0.705	<.001	<.001	3	3
GBM	HBA2 →	+1.747	+1.962	.006	.001	3	3
LSCC	HBB →	+1.892	+0.746	<.001	<.001	3	3
BRCA	TP53TG1 →	+0.512	+0.517	.002	.002	3	2
HNSC	CCL20 →	+2.120	+0.816	.001	<.001	3	2
HNSC	RBMS1 →	-0.744	-0.636	.008	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,552 associations by consensus.

CREB3L4 vs RUVBL1 — BRCA

Explore this scatter interactively →