CREB3L2

Across TCGA patient cohorts, CREB3L2 mutation is significantly associated with the RNA expression of many other genes, with 3,901 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CREB3L2-associated genes across cancer lineages are HIRIP3, RNA5SP468, and RNU6-246P. Each is linked with CREB3L2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CREB3L2-to-partner and partner-to-CREB3L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HIRIP3 grouped by CREB3L2-low versus CREB3L2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CREB3L2→partner) and Y-score (partner→CREB3L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HIRIP3 →	+0.354	+2.447	.005	.001	3	3
SKCM	RNA5SP468 →	+0.229	+2.809	<.001	.004	3	3
CESC	RNU6-246P →	+0.452	+5.306	<.001	.006	3	2
CESC	RN7SL447P →	+0.230	+5.201	<.001	.007	3	2
UCEC	INTS4 →	+0.297	+3.098	.002	<.001	3	2
UCEC	CPSF7 →	+0.299	+1.942	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,901 associations by consensus.

HIRIP3 by CREB3L2 expression — UCEC

Explore this box plot interactively →