CREB3L2

Across TCGA cell cohorts, CREB3L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,854 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CREB3L2-associated GO terms across cancer lineages are Positive regulation of protein exit from endoplasmic reticulum, Regulation of protein exit from endoplasmic reticulum, and Golgi vesicle transport. Each is linked with CREB3L2 in more than 17 cancer types. Because this analysis shows association rather than direction, both CREB3L2-to-partner and partner-to-CREB3L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein exit from endoplasmic reticulum grouped by CREB3L2-low versus CREB3L2-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CREB3L2→partner) and Y-score (partner→CREB3L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of protein exit from endoplasmic reticulum →	+0.140	+1.770	<.001	<.001	3	18
BONE	Regulation of protein exit from endoplasmic reticulum →	+0.148	+1.223	.003	.002	3	15
OESOPHAGUS	Golgi vesicle transport →	+0.098	+1.143	<.001	<.001	3	14
BONE	Cotranslational protein targeting to membrane →	+0.122	+1.037	<.001	<.001	3	14
OESOPHAGUS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.099	+1.074	.002	<.001	3	14
KIDNEY	COPII-coated vesicle cargo loading →	+0.123	+1.308	<.001	.004	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,854 associations by consensus.

Positive regulation of protein exit from endoplasmic reticulum by CREB3L2 expression — KIDNEY

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