CREB3L2

Across TCGA cell cohorts, CREB3L2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CREB3L2-associated genes across cancer lineages are ZCCHC13, OR51T1, and GSG1L2. Each is linked with CREB3L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CREB3L2-to-partner and partner-to-CREB3L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZCCHC13 grouped by CREB3L2-low versus CREB3L2-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CREB3L2→partner) and Y-score (partner→CREB3L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	ZCCHC13 →	+0.025	+4.285	<.001	.007	3	1
BLOOD_Leukemia	OR51T1 →	+0.071	+4.922	<.001	.009	3	1
BLOOD_Leukemia	GSG1L2 →	+0.058	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ZCCHC13 by CREB3L2 expression — STOMACH

Explore this box plot interactively →