CREB3L1

Across TCGA patient cohorts, CREB3L1 mutation is significantly associated with the RNA expression of many other genes, with 1,778 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CREB3L1-associated genes across cancer lineages are CORT, RN7SL504P, and RNU6ATAC29P. Each is linked with CREB3L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CREB3L1-to-partner and partner-to-CREB3L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CORT grouped by CREB3L1-low versus CREB3L1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CREB3L1→partner) and Y-score (partner→CREB3L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CORT →	+0.314	+3.223	.003	.009	3	3
SKCM	RN7SL504P →	+0.034	+3.900	<.001	.008	3	2
HNSC	RNU6ATAC29P →	+0.369	+5.182	<.001	.007	3	2
UCEC	C1orf174 →	+0.477	+3.711	.003	<.001	3	2
UCEC	LIN7C →	+0.632	+3.721	.004	<.001	3	2
UCEC	CENPU →	+0.943	+3.732	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,778 associations by consensus.

CORT by CREB3L1 expression — COAD

Explore this box plot interactively →