CREB3L1

Across TCGA cell cohorts, CREB3L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,122 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CREB3L1-associated GO terms across cancer lineages are Regulation of muscle hypertrophy, Response to fluoride, and Transposable element silencing by piRNA-mediated heterochromatin formation. Each is linked with CREB3L1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CREB3L1-to-partner and partner-to-CREB3L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of muscle hypertrophy grouped by CREB3L1-low versus CREB3L1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CREB3L1→partner) and Y-score (partner→CREB3L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of muscle hypertrophy →	+0.145	+3.982	<.001	<.001	3	10
BONE	Response to fluoride →	+0.226	+3.796	<.001	<.001	3	10
LIVER	Transposable element silencing by piRNA-mediated heterochromatin formation →	+1.772	+2.618	<.001	.004	3	10
LIVER	Regulation of collagen biosynthetic process →	+0.197	+3.707	<.001	<.001	3	10
LIVER	Negative regulation of mRNA catabolic process →	-0.070	-3.769	.004	<.001	3	9
BONE	RNA stabilization →	-0.078	-4.507	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,122 associations by consensus.

Regulation of muscle hypertrophy by CREB3L1 expression — BONE

Explore this box plot interactively →