CREB3

mass-spec protein — tumor vs normal
Tumor vs Normalmass-specBox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, CREB3 mass-spec protein differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of CREB3’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where CREB3 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types CREB3 is over-expressed in tumor.

LUAD are the cancer types where CREB3 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CREB3 mass-spec protein (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LUADAllAll+0.371.0371view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

CREB3–LUAD

Tumor-vs-normal mass-spec protein box plot for CREB3 in LUAD.

Open the LUAD breakdown →

Exploration