CRCT1

Across TCGA patient cohorts, CRCT1 RNA expression is significantly associated with the RNA expression of many other genes, with 8,810 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible CRCT1-associated genes across cancer lineages are SPRR3, SPRR1B, and SPRR1A. Each is linked with CRCT1 in more than 26 cancer types. Because this analysis shows association rather than direction, both CRCT1-to-partner and partner-to-CRCT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRCT1 versus SPRR3 in ESCA, with a Pearson correlation of 0.77.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRCT1→partner) and Y-score (partner→CRCT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	SPRR3 →	+6.217	+4.575	<.001	<.001	3	27
ESCA	SPRR1B →	+7.782	+5.499	<.001	<.001	3	26
ESCA	SPRR1A →	+7.325	+5.448	<.001	<.001	3	25
ESCA	KRT6C →	+6.760	+5.520	<.001	<.001	3	22
ESCA	RPTN →	+1.713	+4.464	<.001	<.001	3	22
ESCA	SPRR2A →	+7.063	+5.259	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,810 associations by consensus.

CRCT1 vs SPRR3 — ESCA

Explore this scatter interactively →