CRCP

Across TCGA cell cohorts, CRCP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,063 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CRCP-associated GO terms across cancer lineages are Cytosolic ribosome assembly, Positive regulation of isotype switching to IgG isotypes, and Peptidyl-glutamic acid carboxylation. Each is linked with CRCP in more than 11 cancer types. Because this analysis shows association rather than direction, both CRCP-to-partner and partner-to-CRCP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic ribosome assembly grouped by CRCP-low versus CRCP-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRCP→partner) and Y-score (partner→CRCP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Cytosolic ribosome assembly →	+0.112	+0.530	<.001	.002	3	11
BLOOD_Lymphoma	Positive regulation of isotype switching to IgG isotypes →	+0.117	+0.713	.001	.001	3	11
BONE	Peptidyl-glutamic acid carboxylation →	+0.111	+0.630	<.001	<.001	2	12
BONE	Protein carboxylation →	+0.111	+0.630	<.001	<.001	2	12
BLOOD_Lymphoma	Nuclear export →	+0.078	+1.049	<.001	<.001	3	10
BREAST	Endocytic recycling →	+0.059	+0.883	.003	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,063 associations by consensus.

Cytosolic ribosome assembly by CRCP expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →