CRB1

Across TCGA patient cohorts, CRB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,008 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRB1-associated proteins across cancer lineages are RO60, KBTBD11, and TBC1D2. Each is linked with CRB1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CRB1-to-partner and partner-to-CRB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRB1 versus RO60 in OV, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRB1→partner) and Y-score (partner→CRB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RO60 →	+0.254	+0.125	<.001	.001	3	4
GBM	KBTBD11 →	+0.418	+0.962	.004	.001	3	4
CCRCC	TBC1D2 →	-0.419	-0.267	.001	.002	3	4
OV	IFT52 →	+0.453	+0.142	<.001	<.001	3	4
CCRCC	SEC11A →	-0.330	-0.289	<.001	<.001	3	3
GBM	KYNU →	-0.545	-1.128	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,008 associations by consensus.

CRB1 vs RO60 — OV

Explore this scatter interactively →