CRB1

Across TCGA patient cohorts, CRB1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,415 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRB1-associated genes across cancer lineages are CZIB, SERTAD4, and UPK1A. Each is linked with CRB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CRB1-to-partner and partner-to-CRB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRB1 versus CZIB in UCEC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRB1→partner) and Y-score (partner→CRB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CZIB →	+0.449	+0.664	.007	.007	3	2
CCRCC	SERTAD4 →	+1.225	+0.175	<.001	.009	3	2
LUAD	UPK1A →	-0.187	-0.865	.001	.001	3	1
LUAD	GSDME →	-0.509	-0.720	.002	.007	3	1
LUAD	MINDY4 →	-0.346	-0.704	.004	.008	3	1
LUAD	WASL →	-0.406	-1.085	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,415 associations by consensus.

CRB1 vs CZIB — UCEC

Explore this scatter interactively →