CRAT

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CRAT RNA expression is significantly associated with the protein abundance of many other proteins, with 11,778 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CRAT-associated proteins across cancer lineages are PTPA, SEC16A, and COQ10B. Each is linked with CRAT in more than 5 cancer types. Because this analysis shows association rather than direction, both CRAT-to-partner and partner-to-CRAT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRAT versus PTPA in GBM, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRAT→partner) and Y-score (partner→CRAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMPTPA →+0.319+0.609.001.00136
BRCASEC16A →+0.269+1.173<.001<.00135
UCECCOQ10B →+0.476+1.172.007<.00135
OVRABL6 →+0.359+0.957.002.00534
UCECDDX52 →-0.347-1.073.007.00634
UCECGOLGA1 →+0.282+1.217<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,778 associations by consensus.

CRAT vs PTPA — GBM

Per-sample scatter of CRAT vs PTPA in GBM (Pearson r = 0.56).

Explore this scatter interactively →

Exploration