CRAT

Across TCGA patient cohorts, CRAT protein abundance is significantly associated with the RNA expression of many other genes, with 11,379 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CRAT-associated genes across cancer lineages are RAD51AP1, AMOT, and MED10. Each is linked with CRAT in more than 4 cancer types. Because this analysis shows association rather than direction, both CRAT-to-partner and partner-to-CRAT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRAT versus RAD51AP1 in BRCA, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRAT→partner) and Y-score (partner→CRAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RAD51AP1 →	-1.280	-0.808	<.001	.001	3	5
HNSC	AMOT →	+1.257	+0.699	<.001	.001	3	4
PDAC	MED10 →	-0.327	-0.322	.001	<.001	3	4
COAD	UBASH3B →	-0.605	-0.610	<.001	.001	3	4
BRCA	ALDH4A1 →	+0.820	+0.691	<.001	<.001	3	4
CCRCC	AZGP1 →	+1.501	+0.279	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,379 associations by consensus.

CRAT vs RAD51AP1 — BRCA

Explore this scatter interactively →