CRAT

Across TCGA cell cohorts, CRAT RNA expression is significantly associated with the go_rna of many other GO terms, with 4,297 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CRAT-associated GO terms across cancer lineages are Lipid modification, Carnitine metabolic process, CoA-linked, and Short-chain fatty acid metabolic process. Each is linked with CRAT in more than 11 cancer types. Because this analysis shows association rather than direction, both CRAT-to-partner and partner-to-CRAT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lipid modification grouped by CRAT-low versus CRAT-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRAT→partner) and Y-score (partner→CRAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Lipid modification →	+0.057	+1.674	.002	<.001	3	12
SOFT_TISSUE	Carnitine metabolic process, CoA-linked →	+0.341	+1.493	<.001	<.001	3	12
BREAST	Short-chain fatty acid metabolic process →	+0.147	+1.875	<.001	.004	3	11
LUNG_NSCLC_LUAD	Lipid oxidation →	+0.070	+1.272	<.001	<.001	3	11
BREAST	Fatty acid beta-oxidation using acyl-CoA oxidase →	+0.134	+2.682	<.001	<.001	3	10
LUNG_SCLC	Amino-acid betaine metabolic process →	+0.104	+1.528	.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,297 associations by consensus.

Lipid modification by CRAT expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →