CRAMP1

Across TCGA cell cohorts, CRAMP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,069 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CRAMP1-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, Positive regulation of intracellular estrogen receptor signaling pathway, and Regulation of DNA repair. Each is linked with CRAMP1 in more than 16 cancer types. Because this analysis shows association rather than direction, both CRAMP1-to-partner and partner-to-CRAMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair grouped by CRAMP1-low versus CRAMP1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRAMP1→partner) and Y-score (partner→CRAMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of double-strand break repair →	+0.094	+1.197	<.001	<.001	3	17
URINARY_TRACT	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.187	+1.096	<.001	<.001	3	17
BREAST	Regulation of DNA repair →	+0.056	+1.094	<.001	<.001	3	17
BONE	Viral translational termination-reinitiation →	+0.110	+1.382	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Signal transduction in response to DNA damage →	+0.079	+0.986	<.001	.001	3	16
BONE	Negative regulation of DNA-templated transcription initiation →	+0.164	+1.146	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,069 associations by consensus.

Positive regulation of double-strand break repair by CRAMP1 expression — SOFT_TISSUE

Explore this box plot interactively →