CRAMP1

Across TCGA cell cohorts, CRAMP1 mutation is significantly associated with the RNA expression of many other genes, with 284 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CRAMP1-associated genes across cancer lineages are TECTB, OR5H2, and CYP4A11. Each is linked with CRAMP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CRAMP1-to-partner and partner-to-CRAMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TECTB grouped by CRAMP1-low versus CRAMP1-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRAMP1→partner) and Y-score (partner→CRAMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	TECTB →	+0.942	+4.011	<.001	.009	3	2
STOMACH	OR5H2 →	+0.207	+4.285	<.001	.007	3	2
BLOOD_Leukemia	CYP4A11 →	+0.021	+3.705	.004	.007	3	2
LARGE_INTESTINE	LIPN →	+0.009	+2.208	<.001	.002	3	2
OESOPHAGUS	METTL21C →	+0.027	+4.017	<.001	.007	3	1
PANCREAS	PRLHR →	+0.006	+4.786	.007	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 284 associations by consensus.

TECTB by CRAMP1 expression — PANCREAS

Explore this box plot interactively →