CRACR2A

Across TCGA patient cohorts, CRACR2A protein abundance is significantly associated with the RNA expression of many other genes, with 14,058 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CRACR2A-associated genes across cancer lineages are XBP1, CYTH3, and ELAPOR1. Each is linked with CRACR2A in more than 4 cancer types. Because this analysis shows association rather than direction, both CRACR2A-to-partner and partner-to-CRACR2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRACR2A versus XBP1 in BRCA, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRACR2A→partner) and Y-score (partner→CRACR2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	XBP1 →	+1.545	+0.507	<.001	<.001	3	5
LUAD	CYTH3 →	-0.854	-0.454	<.001	<.001	3	5
BRCA	ELAPOR1 →	+1.832	+0.522	<.001	<.001	3	5
LSCC	NRM →	-0.414	-0.314	<.001	<.001	3	4
BRCA	DNAJC2 →	-0.473	-0.629	<.001	<.001	3	4
HNSC	IPPK →	-0.693	-0.312	.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,058 associations by consensus.

CRACR2A vs XBP1 — BRCA

Explore this scatter interactively →