CRACR2A

Across TCGA cell cohorts, CRACR2A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,118 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CRACR2A-associated GO terms across cancer lineages are Maturation of SSU-rRNA, Mitotic chromosome movement towards spindle pole, and rRNA transcription. Each is linked with CRACR2A in more than 9 cancer types. Because this analysis shows association rather than direction, both CRACR2A-to-partner and partner-to-CRACR2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of SSU-rRNA grouped by CRACR2A-low versus CRACR2A-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRACR2A→partner) and Y-score (partner→CRACR2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Maturation of SSU-rRNA →	+0.091	+1.904	<.001	<.001	3	10
KIDNEY	Mitotic chromosome movement towards spindle pole →	+0.104	+1.661	.002	.002	3	9
BLOOD_Myeloma	rRNA transcription →	+0.087	+1.105	<.001	.003	3	9
BLOOD_Lymphoma	Ribosome biogenesis →	+0.093	+1.194	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	DNA topological change →	+0.093	+0.980	<.001	.005	3	9
STOMACH	Microtubule depolymerization →	+0.112	+1.943	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,118 associations by consensus.

Maturation of SSU-rRNA by CRACR2A expression — LUNG_SCLC

Explore this box plot interactively →