Across TCGA patient cohorts, CRACDL protein abundance is significantly associated with the RNA expression of many other genes, with 14,853 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CRACDL-associated genes across cancer lineages are RNF183, CAPN13, and NCAPH. Each is linked with CRACDL in more than 4 cancer types. Because this analysis shows association rather than direction, both CRACDL-to-partner and partner-to-CRACDL results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRACDL→partner) and Y-score (partner→CRACDL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNF183 →	+1.271	+0.623	<.001	<.001	3	5
BRCA	CAPN13 →	+1.740	+0.568	<.001	<.001	3	5
OV	NCAPH →	-0.797	-0.612	<.001	.001	3	4
BRCA	TICRR →	-0.697	-0.552	<.001	<.001	3	4
UCEC	ENKUR →	+1.235	+0.407	.001	.001	3	4
UCEC	FANCB →	-0.830	-0.485	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,853 associations by consensus.

Exploration

CRACDL survival (RNA) · tumor vs normal (RNA) · all CRACDL data types