CRACD

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CRACD protein abundance is significantly associated with the RNA expression of many other genes, with 15,532 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRACD-associated genes across cancer lineages are C7, SVEP1, and ZCCHC24. Each is linked with CRACD in more than 5 cancer types. Because this analysis shows association rather than direction, both CRACD-to-partner and partner-to-CRACD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRACD versus C7 in CCRCC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRACD→partner) and Y-score (partner→CRACD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCC7 →+2.503+0.508<.001<.00136
CCRCCSVEP1 →+1.174+0.510<.001<.00136
BRCAZCCHC24 →+0.916+0.466<.001<.00136
BRCALAMA2 →+1.065+0.451<.001.00236
UCECCPED1 →+0.747+0.387<.001<.00135
UCECSFRP4 →+2.095+0.477<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,532 associations by consensus.

CRACD vs C7 — CCRCC

Per-sample scatter of CRACD vs C7 in CCRCC (Pearson r = 0.39).

Explore this scatter interactively →

Exploration