CRABP2

Across TCGA pan-cancer cohorts, CRABP2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CRABP2 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CRABP2 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CRABP2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CCRCC show a favorable association.

HNSC, PDAC, and CCRCC are the cancer types where CRABP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	1.000	0.344	.009	35	view →
PDAC	DFS	Tertile	II,III,IV	0.592	0.867	.001	35	view →
CCRCC	DFS	Median	All	0.847	0.621	.011	9	view →
LUAD	OS	Median	All	0.668	0.939	.010	4	view →
LSCC	DFS	Tertile	All	0.480	1.000	.018	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CRABP2–HNSC (OS)

Open the HNSC breakdown →