CRABP1

Across TCGA pan-cancer cohorts, CRABP1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated CRABP1 data layer compared with 2 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CRABP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CRABP1 expression acts as an unfavorable survival marker, although some lineages such as DLBC and THCA show a favorable association.

UCEC, DLBC, and CESC are the cancer types where CRABP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.780	0.895	<.001	92	view →
DLBC	DFS	Tertile	All	1.000	0.371	<.001	63	view →
CESC	DFS	Median	All	0.651	0.819	<.001	56	view →
LGG	DFS	Quartile	All	0.623	0.809	<.001	33	view →
KIRC	OS	Tertile	II,III,IV	0.419	0.598	.004	24	view →
THCA	DFS	Median	IV	1.000	0.563	.006	23	view →
LUSC	OS	Median	III,IV	0.260	0.823	.012	22	view →
KIRP	DFS	Median	All	0.798	0.974	.007	19	view →
HNSC	OS	Tertile	III,IV	0.826	0.665	.007	17	view →
ACC	DFS	Median	All	0.326	0.565	.037	17	view →
ESCA	DFS	Tertile	III,IV	0.232	0.448	.002	15	view →
OV	OS	Median	IV	0.756	0.493	.003	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

CRABP1–UCEC (DFS)

Open the UCEC breakdown →