Across TCGA patient cohorts, CR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,528 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CR1-associated proteins across cancer lineages are PTPRC, STX11, and WAS. Each is linked with CR1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CR1-to-partner and partner-to-CR1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CR1→partner) and Y-score (partner→CR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PTPRC →	+0.836	+1.404	<.001	<.001	3	10
UCEC	STX11 →	+0.890	+1.020	<.001	<.001	3	10
GBM	WAS →	+0.753	+1.355	<.001	<.001	3	10
UCEC	CYBB →	+0.797	+0.637	.001	.003	3	10
GBM	DOCK2 →	+0.720	+1.340	<.001	<.001	3	10
GBM	DOK2 →	+0.945	+1.339	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,528 associations by consensus.

Exploration

CR1 survival (RNA) · tumor vs normal (RNA) · all CR1 data types