Across TCGA patient cohorts, CR1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,277 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CR1-associated genes across cancer lineages are CSF3R, CEACAM3, and FPR2. Each is linked with CR1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CR1-to-partner and partner-to-CR1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CR1→partner) and Y-score (partner→CR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CSF3R →	+1.891	+1.851	<.001	<.001	3	6
PDAC	CEACAM3 →	+0.939	+0.803	<.001	<.001	3	6
GBM	FPR2 →	+1.977	+1.359	<.001	<.001	3	6
GBM	MEFV →	+0.942	+1.023	<.001	<.001	3	5
COAD	IL1B →	+2.009	+0.761	<.001	.002	3	5
GBM	LILRB2 →	+1.162	+0.976	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,277 associations by consensus.

Exploration

CR1 survival (RNA) · tumor vs normal (RNA) · all CR1 data types