CPXM2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CPXM2 mutation is significantly associated with the RNA expression of many other genes, with 2,596 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPXM2-associated genes across cancer lineages are LINC01852, RNA5SP453, and RASL12. Each is linked with CPXM2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CPXM2-to-partner and partner-to-CPXM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01852 grouped by CPXM2-low versus CPXM2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPXM2→partner) and Y-score (partner→CPXM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMLINC01852 →-0.295-1.887<.001.00133
CESCRNA5SP453 →+0.209+3.891<.001.00233
LUADRASL12 →-0.656-2.807.003.00333
LUADCACYBP →+0.684+2.819<.001.00133
LUADSTARD8 →-0.651-3.656<.001.00133
LUADPSMB6 →+0.532+2.842<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,596 associations by consensus.

LINC01852 by CPXM2 expression — SKCM

Box plot of LINC01852 in CPXM2-low vs CPXM2-high samples in SKCM.

Explore this box plot interactively →

Exploration