CPXM2

Across TCGA patient cohorts, CPXM2 mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPXM2-associated genes across cancer lineages are PKC-b-II_pS660, mTOR_pS2448, and ATM. Each is linked with CPXM2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CPXM2-to-partner and partner-to-CPXM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PKC-b-II_pS660 grouped by CPXM2-low versus CPXM2-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPXM2→partner) and Y-score (partner→CPXM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	PKC-b-II_pS660 →	-0.428	-2.321	.006	.034	3	3
UCEC	mTOR_pS2448 →	-0.114	-2.074	.018	.004	3	3
UCEC	ATM →	-0.357	-1.222	.015	.035	3	3
UCEC	Cyclin-B1 →	+0.477	+2.115	.008	.016	3	2
STAD	FASN →	+0.586	+3.015	.001	.018	3	2
STAD	Fibronectin →	+0.351	+2.342	.022	.019	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

PKC-b-II_pS660 by CPXM2 expression — STAD

Explore this box plot interactively →