CPXM2

Across TCGA cell cohorts, CPXM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 629 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CPXM2-associated GO terms across cancer lineages are Negative regulation of endoplasmic reticulum unfolded protein response, Golgi vesicle transport, and Peptidyl-lysine acetylation. Each is linked with CPXM2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CPXM2-to-partner and partner-to-CPXM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of endoplasmic reticulum unfolded protein response grouped by CPXM2-low versus CPXM2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPXM2→partner) and Y-score (partner→CPXM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Negative regulation of endoplasmic reticulum unfolded protein response →	+0.056	+1.822	<.001	<.001	3	4
SKIN	Golgi vesicle transport →	+0.037	+1.357	.002	.006	3	4
PANCREAS	Peptidyl-lysine acetylation →	+0.071	+0.026	<.001	.004	3	4
KIDNEY	Protein exit from endoplasmic reticulum →	+0.086	+0.072	.001	.009	2	5
KIDNEY	Glycerophospholipid biosynthetic process →	+0.034	+0.064	.004	.005	3	4
SKIN	Myotube differentiation →	+0.072	+1.710	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 629 associations by consensus.

Negative regulation of endoplasmic reticulum unfolded protein response by CPXM2 expression — SKIN

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