CPXM2

Across TCGA cell cohorts, CPXM2 mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CPXM2-associated genes across cancer lineages are OR9K2, CST9, and AADACL2. Each is linked with CPXM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPXM2-to-partner and partner-to-CPXM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR9K2 grouped by CPXM2-low versus CPXM2-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPXM2→partner) and Y-score (partner→CPXM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	OR9K2 →	+0.172	+4.017	.003	.007	3	1
BLOOD_Leukemia	CST9 →	+0.012	+5.201	<.001	.006	3	1
BLOOD_Leukemia	AADACL2 →	+0.025	+4.922	<.001	.009	3	1
BLOOD_Lymphoma	ECE2 →	+0.038	+3.736	.002	.008	3	1
LARGE_INTESTINE	REG3A →	+1.678	+3.584	.001	.003	3	1
LARGE_INTESTINE	REG1B →	+2.243	+2.518	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

OR9K2 by CPXM2 expression — OESOPHAGUS

Explore this box plot interactively →