CPXM1

Across TCGA patient cohorts, CPXM1 mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPXM1-associated genes across cancer lineages are ATM, Cyclin-B1, and ASNS. Each is linked with CPXM1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CPXM1-to-partner and partner-to-CPXM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by CPXM1-low versus CPXM1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPXM1→partner) and Y-score (partner→CPXM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.557	-1.777	<.001	.002	3	3
UCEC	Cyclin-B1 →	+0.612	+3.700	<.001	.001	3	3
COAD	ASNS →	+0.570	+2.815	.008	.036	3	2
COAD	Caspase-7-cleavedD198 →	+1.391	+2.824	.001	.034	3	2
UCEC	FoxM1 →	+0.216	+1.777	.009	.002	3	2
UCEC	Gab2 →	+0.259	+1.289	.023	.023	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

ATM by CPXM1 expression — UCEC

Explore this box plot interactively →