CPXM1

Across TCGA cell cohorts, CPXM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,515 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CPXM1-associated GO terms across cancer lineages are Transcription initiation at RNA polymerase II promoter, Regulation of double-strand break repair, and RNA splicing, via transesterification reactions with bulged adenosine as nucleophile. Each is linked with CPXM1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CPXM1-to-partner and partner-to-CPXM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription initiation at RNA polymerase II promoter grouped by CPXM1-low versus CPXM1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPXM1→partner) and Y-score (partner→CPXM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Transcription initiation at RNA polymerase II promoter →	+0.066	+2.338	.001	<.001	3	8
BONE	Regulation of double-strand break repair →	+0.059	+1.596	<.001	.001	3	7
BONE	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.052	+1.408	.001	.007	2	8
BONE	mRNA splicing, via spliceosome →	+0.052	+1.408	.001	.007	2	8
BONE	Mitotic cell cycle phase transition →	+0.066	+1.806	.001	<.001	3	7
BONE	Protein-RNA complex organization →	+0.073	+1.649	.003	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,515 associations by consensus.

Transcription initiation at RNA polymerase II promoter by CPXM1 expression — LUNG_SCLC

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