CPXM1

Across TCGA cell cohorts, CPXM1 mutation is significantly associated with the RNA expression of many other genes, with 111 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CPXM1-associated genes across cancer lineages are KIR2DS4, OR2M5, and OR52A1. Each is linked with CPXM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPXM1-to-partner and partner-to-CPXM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KIR2DS4 grouped by CPXM1-low versus CPXM1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPXM1→partner) and Y-score (partner→CPXM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	KIR2DS4 →	+0.116	+5.029	<.001	.006	3	1
SKIN	OR2M5 →	+0.016	+4.437	<.001	.004	3	1
SKIN	OR52A1 →	+0.052	+4.196	<.001	.002	3	1
SKIN	ANKRD63 →	+0.093	+3.684	<.001	.009	3	1
LARGE_INTESTINE	MIOX →	+0.237	+3.087	.003	.006	3	1
LARGE_INTESTINE	RHBDL1 →	+0.798	+2.502	.006	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 111 associations by consensus.

KIR2DS4 by CPXM1 expression — LUNG_SCLC

Explore this box plot interactively →