CPVL

Across TCGA cell cohorts, CPVL RNA expression is significantly associated with the go_rna of many other GO terms, with 4,485 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CPVL-associated GO terms across cancer lineages are Proton transmembrane transport, Oxidative phosphorylation, and DNA-templated transcription initiation. Each is linked with CPVL in more than 9 cancer types. Because this analysis shows association rather than direction, both CPVL-to-partner and partner-to-CPVL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proton transmembrane transport grouped by CPVL-low versus CPVL-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPVL→partner) and Y-score (partner→CPVL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Proton transmembrane transport →	+0.069	+1.549	.003	.004	3	10
LIVER	Oxidative phosphorylation →	+0.073	+3.050	<.001	<.001	3	10
BONE	DNA-templated transcription initiation →	+0.074	+2.753	.001	.004	3	9
BONE	Transcription initiation at RNA polymerase II promoter →	+0.071	+3.177	.002	<.001	3	9
LUNG_NSCLC_LUSC	Cytoplasmic translation →	+0.064	+1.429	.008	.008	2	10
BONE	RNA splicing, via transesterification reactions →	+0.076	+3.216	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,485 associations by consensus.

Proton transmembrane transport by CPVL expression — LUNG_SCLC

Explore this box plot interactively →